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Notes from P2 Brain
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****** ABSTRACT ******
[[see word doc emailed as a separate file]]
****** Abstract figures ******
– No double line on figure
– Colorization
– Recolorize fn & sl relative to JW/JP subfi
****** JW updates ******
– For main Many schematics going across incl. DW’s network growth
– For abs. Use JP ex. With simplification
****** FN – RCA ******
– Flip graneen v yellow
– Ellipsiods a little faint
****** XS – single cell updates ******
– Brainspan single-cell?
– think about the cell types – collapse cell types + discuss w/ Jim
– add fetal, embryo to brainspan
– make the batch effect suppl. Figure which is diffe.
– determine optimal 100 biomarker, 10 biomarker genes to get the best R^2 [see board pic]
– what about the opc result for the gender disparities – ask Jim
– make a schematic for the 85%
– Cell type QTL – vs all variants like transQTL
****** MG’s suggestions for main text ******
– did we really detect brain-specific? Or brain-active?
– “mega” analysis — remove
– with respect to eTWAS: change if possible
– 1945 — put real number in text (for individuals)
– with respect to MG’s note “more” — elaborate and be sure to remain consistent across different tissues.
– “JW” — JW agrees with the “three-times” improvement remark
****** Quick updates/notes from meeting ******
– Fri website call Geetha
– SL – Fri. at noon or 1:30
– Jeff Lichtman
– SCREEN – reprocessing of roadmap brain samples
On Wed, Jan 10, 2018 at 8:32 PM, Shi, Xu <xu.shi> wrote: