Tag Archives: bioinformatics

Evogeneao: The Tree of Life

Evogeneao: The Tree of Life
https://www.evogeneao.com/explore/tree-of-life-explorer Nice web tool. Particularly good for interactively #visualizing human #evolution relative to that of other species

NAR Breakthrough Article: denovo-db: a compendium of human de novo variants

.@denovodb: a compendium of [initially ~33K] human de novo variants w. phenotype, freely downloadable as a TSV table

As of July 2016, denovo-db contained 40 different studies and 32,991 de novo variants from 23,098 trios. Database features include basic variant information (chromosome location, change, type); detailed annotation at the transcript and protein levels; severity scores; frequency; validation status; and, most importantly, the phenotype of the individual with the variant.