Decoding the Genomics of Abdominal Aortic Aneurysm
Jingjing Li, Cuiping Pan, Sai Zhang, …, Ronald L. Dalman, Philip S. Tsao, Michael Snyder
I’ll present "Multi-scale deep tensor factorization learns a latent representation of the human epigenome" for tomorrow’s journal club.
This paper from Noble’s lab presents a method to impute human epigenome, and demonstrated its usage in broad context.
This work was preceded by their previous work known as PREDICTD, which I will also discuss briefly tomorrow.
You can find the bioRxiv preprint here.
Nature Communications paper:
3D clusters of somatic mutations…reveal numerous rare mutations as functional targets
https://GenomeMedicine.BiomedCentral.com/articles/10.1186/s13073-016-0393-x Introduces 3DHotSpots, which is one of a number of recent approaches (incl. CLUMPS, Hotspot3D, Mutation3D & HotMAPS) for finding groupings of somatic SNVs via structure
Highly parallel direct RNA sequencing on an array of nanoporeshttps://www.nature.com/articles/nmeth.4577