3D clusters of somatic mutations…reveal numerous rare mutations as functional targets
https://GenomeMedicine.BiomedCentral.com/articles/10.1186/s13073-016-0393-x Introduces 3DHotSpots, which is one of a number of recent approaches (incl. CLUMPS, Hotspot3D, Mutation3D & HotMAPS) for finding groupings of somatic SNVs via structure
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1) Journal clubs
subject: Journal Club by MG on “Methylation from Environmental Toxins Causes DNA Knots & Protein Coils,” Nurture
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In this week’s jclub, I will discuss the two papers: